Bio-identical vs synthetic hormones — what’s the difference?
If you’re exploring hormone therapy, the terminology can feel confusing, so let’s break it down.
🔹 Bio-identical hormones (in regulated prescription products) are chemically identical to the hormones your body makes. They’re well-studied, effective, and often have favourable safety profiles — especially estradiol patches/gels and micronised progesterone.
🔹 Synthetic hormones are similar, but not identical. They can still work well, but may have different side-effect or risk profiles depending on the type and formulation.
🔹 Compounded bio-identical hormones are custom-made and not regulated the same way — meaning dosing and quality can vary. Most specialists prefer regulated, pharmaceutical-grade options instead.
The bottom line: it’s less about the label and more about choosing the safest, most evidence-based option for you.
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